Daniil Medvedev’s Rome Open title defence came to an end at the last-16 stage on Tuesday after the world No 4 was knocked out in straight sets by Tommy Paul, 6-1, 6-4.
Second seed Medvedev has never successfully defended an ATP Tour crown and was well below his best, stunned by American Paul who claimed his first win against the former US Open champion.
Paul will play Hubert Hurkacz, who knocked out Rafael Nadal earlier in the tournament, in the quarterfinals.